Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417035 | 0.92 | MAPT (0.44) | LMNAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL9417113 | 0.84 | ALOX5 (0.35) | — | |
| SCHEMBL9417080 | 0.80 | PTGS2 (0.38) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL9417069 | 0.79 | KDM4E (0.43) | ALDH1A1HPGDHSD17B10TSHRMAPT | |
| SCHEMBL9417050 | 0.79 | ALDH1A1 (0.39) | LMNAALDH1A1ALOX15HSD17B10TSHR | |
| SCHEMBL9416939 | 0.78 | PTGS2 (0.37) | MEN1KMT2AHTTMAPTGAA | |
| SCHEMBL9416950 | 0.77 | KDM4E (0.43) | LMNAPOLBALDH1A1ALOX15MAPK1 | |
| SCHEMBL9417018 | 0.76 | ALOX5 (0.35) | — | |
| SCHEMBL9416986 | 0.75 | HTT (0.41) | LMNAPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL9417007 | 0.74 | KDM4E (0.36) | HSD17B10SMN1; SMN2SIGMAR1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |