Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417069 | 0.91 | KDM4E (0.43) | KDM4EGAAMAPTALOX5PTGS1 | |
| SCHEMBL9416986 | 0.89 | HTT (0.41) | KDM4EMAPTALOX5PTGS1PTGS2 | |
| SCHEMBL9417050 | 0.86 | ALDH1A1 (0.39) | KDM4EGAAMAPTALOX5PTGS1 | |
| SCHEMBL9416939 | 0.85 | PTGS2 (0.37) | KDM4EGAAMAPTALOX5PTGS1 | |
| SCHEMBL9417080 | 0.85 | PTGS2 (0.38) | KDM4EGAAMAPTALOX5PTGS1 | |
| SCHEMBL9417017 | 0.78 | DRD2 (0.40) | ALOX5PTGS1PTGS2APP | |
| SCHEMBL9416974 | 0.77 | ALOX5 (0.32) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9417117 | 0.76 | ALOX5 (0.32) | KDM4EGAAMAPTALOX5PTGS1 | |
| SCHEMBL9416952 | 0.74 | LMNA (0.40) | KDM4EGAAMAPTSMN1; SMN2SIGMAR1 | |
| SCHEMBL9417113 | 0.73 | ALOX5 (0.35) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |