Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416939 | 0.95 | PTGS2 (0.37) | PTGS2PTGS1ALOX5G6PC1PTPN1 | |
| SCHEMBL9416986 | 0.91 | HTT (0.41) | PTGS2PTGS1ALOX5G6PC1KDM4E | |
| SCHEMBL9417050 | 0.90 | ALDH1A1 (0.39) | PTGS2PTGS1ALOX5G6PC1TTR | |
| SCHEMBL9417069 | 0.90 | KDM4E (0.43) | PTGS2PTGS1ALOX5G6PC1TTR | |
| SCHEMBL9417017 | 0.87 | DRD2 (0.40) | PTGS2PTGS1ALOX5 | |
| SCHEMBL9416974 | 0.86 | ALOX5 (0.32) | PTGS2PTGS1ALOX5 | |
| SCHEMBL9417007 | 0.85 | KDM4E (0.36) | PTGS2PTGS1ALOX5KDM4EGAA | |
| SCHEMBL9417117 | 0.82 | ALOX5 (0.32) | PTGS2PTGS1ALOX5G6PC1TTR | |
| SCHEMBL9416952 | 0.80 | LMNA (0.40) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL9417018 | 0.79 | ALOX5 (0.35) | PTGS2PTGS1ALOX5TTRDEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |