Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417069 | 0.92 | KDM4E (0.43) | ALDH1A1TSHRMAPTALOX5PTGS1 | |
| SCHEMBL9417080 | 0.90 | PTGS2 (0.38) | MAPTALOX5PTGS1PTGS2GAA | |
| SCHEMBL9416939 | 0.88 | PTGS2 (0.37) | MAPTALOX5PTGS1PTGS2GAA | |
| SCHEMBL9417007 | 0.86 | KDM4E (0.36) | MAPTALOX5PTGS1PTGS2GAA | |
| SCHEMBL9416986 | 0.85 | HTT (0.41) | ALDH1A1TSHRLMNAMAPTALOX5 | |
| SCHEMBL9417017 | 0.81 | DRD2 (0.40) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9417117 | 0.81 | ALOX5 (0.32) | ALDH1A1LMNAMAPTALOX5PTGS1 | |
| SCHEMBL9416974 | 0.80 | ALOX5 (0.32) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9416952 | 0.79 | LMNA (0.40) | ALDH1A1TSHRLMNAMAPTGAA | |
| SCHEMBL9417018 | 0.78 | ALOX5 (0.35) | ALOX5PTGS1PTGS2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |