Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423081 | 0.82 | CCR2 (0.48) | CCR2SOS1PPARGPPARAALDH1A1 | |
| SCHEMBL2845133 | 0.81 | MEN1 (0.50) | CCR2SOS1PPARGPPARAALDH1A1 | |
| SCHEMBL10939339 | 0.80 | MEN1 (0.50) | CCR2SOS1PPARGPPARAALDH1A1 | |
| SCHEMBL2930491 | 0.79 | CCR2 (0.51) | CCR2SOS1PPARGPPARAALDH1A1 | |
| SCHEMBL9679896 | 0.78 | HTR7 (0.48) | PPARGPPARAALDH1A1KDM4EMAPT | |
| SCHEMBL1760912 | 0.78 | CCR2 (0.50) | CCR2SOS1PPARGPPARAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9423364 | 0.78 | HTR7 (0.47) | PPARGPPARAALDH1A1KDM4EMAPT | |
| SCHEMBL14282249 | 0.75 | ALDH1A1 (0.51) | CCR2SOS1PPARGPPARAALDH1A1 | |
| SCHEMBL187309 | 0.75 | MEN1 (0.50) | CCR2SOS1PPARGPPARAALDH1A1 | |
| SCHEMBL10738116 | 0.75 | CCR2 (0.52) | CCR2SOS1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292745-A | Use of 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine derivatives as free radical scavengers | ELF SANOFI (FR) | 1994-03-08 | — | — | US | disclosed |
| EP-0498718-A1 | Use of 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydro-pyridine-derivatives as free radical scavengers | ELF SANOFI (FR) | 1992-08-12 | — | — | EP | disclosed |