Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | AOC1 | P19801 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425715 | 0.80 | SMN1; SMN2 (0.43) | ALOX12LMNAPOLBGAAHTT | |
| SCHEMBL9586194 | 0.80 | LMNA (0.43) | LMNAPOLBGAAHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9425881 | 0.78 | SMN1; SMN2 (0.42) | ALOX12LMNAPOLBGAAHTT | |
| SCHEMBL9425432 | 0.77 | ALDH1A1 (0.45) | LMNAGAAALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9426498 | 0.76 | ALDH1A1 (0.44) | LMNAGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL9456935 | 0.74 | ABCC9 (0.57) | HTTALDH1A1KMT2AABCC9ABCC8 | |
| SCHEMBL9426257 | 0.74 | ALDH1A1 (0.49) | LMNAGAAHTTALDH1A1KMT2A | |
| SCHEMBL6988265 | 0.72 | CYP1A2 (0.41) | GAAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7873436 | 0.71 | CIT (0.42) | GAAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9426618 | 0.71 | HTT (0.51) | ALOX12LMNAGAAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371086-A | Circulatory disorders side effect reduction | THE GREEN CROSS CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0503627-A1 | Aminopyridine compounds | THE GREEN CROSS CORPORATION (JP) | 1992-09-16 | — | — | EP | disclosed |