Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9428802 | 0.99 | KMT2A (0.58) | LMNAMAPK1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9428720 | 0.88 | MEN1 (0.50) | LMNAMAPK1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9428476 | 0.87 | ALDH1A1 (0.58) | LMNAMAPK1SMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9428327 | 0.87 | MEN1 (0.49) | LMNAMAPK1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9429324 | 0.87 | DRD2 (0.56) | HRH3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL9429006 | 0.87 | HRH1 (0.60) | MAPK1SMN1; SMN2KMT2AMEN1HRH3 | |
| SCHEMBL9428590 | 0.86 | DRD2 (0.48) | KMT2AMEN1KCNH2SLC6A2SLC6A4 | |
| SCHEMBL9428742 | 0.86 | HRH1 (0.47) | KMT2AMEN1HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL9428228 | 0.86 | SIGMAR1 (0.55) | HRH3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL9428864 | 0.85 | KDM4E (0.57) | SMN1; SMN2KMT2AMEN1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |