Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 9/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428300 | 0.88 | DPP4 (0.43) | ALDH1A1HTR1AADRA1BADRA1AHTR2A | |
| SCHEMBL9429888 | 0.87 | HTR1A (0.51) | ALDH1A1HTR1AADRA1BADRA1AHTR2A | |
| SCHEMBL9428509 | 0.86 | HTR1A (0.40) | ALDH1A1HTR1AADRA1BADRA1AHTR2A | |
| SCHEMBL9387767 | 0.85 | LMNA (0.52) | ALDH1A1HTR1AADRA1BADRA1AHTR2A | |
| SCHEMBL9428210 | 0.85 | ADRA1B (0.47) | ALDH1A1THRBHTR1AADRA1BADRA1A | |
| SCHEMBL9428955 | 0.82 | ALDH1A1 (0.45) | ALDH1A1THRBHTR1AADRA1BADRA1A | |
| SCHEMBL9429324 | 0.82 | DRD2 (0.56) | HTR1AHTR2ADRD2DRD3TMEM97 | |
| SCHEMBL9383816 | 0.81 | KDM4E (0.47) | ALDH1A1THRBHTR1AHTR2AMEN1 | |
| Oxalic Acid SCHEMBL9388735 | 0.81 | LMNA (0.48) | ALDH1A1HTR1AHTR2AMEN1KMT2A | |
| Oxalic Acid SCHEMBL9388742 | 0.81 | LMNA (0.48) | ALDH1A1HTR1AHTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |