Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095026 | 0.84 | GLA (0.69) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL5952262 | 0.84 | MEN1 (0.61) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL4332370 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL4118526 | 0.83 | MAPT (0.66) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL4119179 | 0.83 | SMN1; SMN2 (0.73) | ALDH1A1SMN1; SMN2MAPTKDM4ENPC1 | |
| SCHEMBL22648479 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL3714311 | 0.81 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL23624082 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL18119753 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL9609808 | 0.80 | SMN1; SMN2 (0.82) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238139-A1 | MODULATORS OF TRYPTOPHAN CATABOLISM | E-THERAPEUTICS PLC (GB) | 2021-08-05 | — | — | US | disclosed |
| US-10556889-B1 | Salvinorin derivatives | Blue Sky Pharmaceuticals, LLC (US) | 2020-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238139-A1 | MODULATORS OF TRYPTOPHAN CATABOLISM | TPH1, KYNU, TPH2 | ALDH1A1 606/4885SMN1; SMN2 3779/4885HPGD 1286/4885 |
| US-10556889-B1 | Salvinorin derivatives | OPRD1, OPRK1, OPRL1 | ALDH1A1 866/4885SMN1; SMN2 1186/4885HPGD 2448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.