Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429935 | 0.81 | MAPT (0.57) | MAPTTSHRLMNAKMT2AMEN1 | |
| SCHEMBL9384406 | 0.78 | LMNA (0.61) | MAPTLMNAKMT2AMEN1CYP1A2 | |
| SCHEMBL9428746 | 0.76 | HRH1 (0.44) | MAPTTSHRLMNAKMT2AMEN1 | |
| Oxalic Acid SCHEMBL9384506 | 0.75 | LMNA (0.57) | MAPTLMNAKMT2AMEN1CYP1A2 | |
| SCHEMBL9428792 | 0.75 | ALOX15 (0.51) | ALOX15TSHRLMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9428577 | 0.74 | ALOX15 (0.50) | ALOX15MAPTTSHRLMNAKMT2A | |
| SCHEMBL9428233 | 0.73 | CACNA1G (0.57) | LMNAALDH1A1HPGD | |
| SCHEMBL9429871 | 0.71 | HRH1 (0.48) | ALOX15MAPTTSHRLMNAKMT2A | |
| SCHEMBL9429270 | 0.71 | TP53 (0.60) | MAPTLMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL9428857 | 0.69 | HRH1 (0.48) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |