Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9428577 | 0.99 | ALOX15 (0.50) | ALOX15MEN1KMT2AADRB1CYP3A4 | |
| SCHEMBL2327539 | 0.81 | ALDH1A1 (0.64) | ALOX15MEN1KMT2AADRB1CYP3A4 | |
| SCHEMBL9429935 | 0.80 | MAPT (0.57) | MEN1KMT2ACYP3A4CYP2D6LMNA | |
| SCHEMBL6261397 | 0.79 | ALOX15 (0.74) | ALOX15MEN1KMT2AADRB1CYP3A4 | |
| SCHEMBL9384406 | 0.76 | LMNA (0.61) | MEN1KMT2ACYP2D6LMNACYP1A2 | |
| SCHEMBL26007622 | 0.76 | ALDH1A1 (0.58) | ALOX15MEN1KMT2AADRB1CYP3A4 | |
| SCHEMBL8556384 | 0.76 | MEN1 (0.60) | ALOX15MEN1KMT2AADRB1CYP3A4 | |
| Pyrrocaine SCHEMBL25718 | 0.76 | MEN1 (0.70) | ALOX15MEN1KMT2AADRB1CYP3A4 | |
| SCHEMBL7435500 | 0.75 | ALDH1A1 (0.57) | ALOX15MEN1KMT2AADRB1CYP3A4 | |
| SCHEMBL9429073 | 0.75 | ALOX15 (0.50) | ALOX15MEN1KMT2ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |