Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 8/20 | 0.60 |
| ▸ | DRD4 | P21917 | 8/20 | 0.60 |
| ▸ | DRD3 | P35462 | 8/20 | 0.60 |
| ▸ | HTR1A | P08908 | 6/20 | 0.58 |
| ▸ | HTR2A | P28223 | 5/20 | 0.58 |
| ▸ | HTR2C | P28335 | 5/20 | 0.58 |
| ▸ | HRH1 | P35367 | 3/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9429271 | 0.99 | TSHR (0.65) | TSHRDRD2DRD4DRD3HTR1A | |
| SCHEMBL9429593 | 0.81 | SOD1 (0.57) | TSHRDRD2DRD4DRD3HTR1A | |
| SCHEMBL9429398 | 0.81 | HTR1A (0.56) | HTR1AHRH1ALDH1A1KMT2A | |
| SCHEMBL9428233 | 0.81 | CACNA1G (0.57) | HTR1AALDH1A1HTR7LMNA | |
| Hydrochloric Acid SCHEMBL9428830 | 0.80 | ALDH1A1 (0.56) | HTR1AHRH1ALDH1A1KMT2A | |
| SCHEMBL9428373 | 0.80 | DRD2 (0.58) | DRD2DRD3HTR1AHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL9428467 | 0.79 | DRD2 (0.57) | DRD2DRD3HTR1AHTR2AHRH1 | |
| SCHEMBL11832182 | 0.79 | DRD2 (0.88) | TSHRDRD2DRD4DRD3HTR1A | |
| SCHEMBL16986166 | 0.79 | TSHR (0.97) | TSHRDRD2DRD4DRD3HTR1A | |
| SCHEMBL9428377 | 0.78 | CCR5 (0.44) | HRH1ALDH1A1MEN1ADRA1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |