Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428870 | 0.89 | HRH3 (0.57) | HRH1HRH2HRH3MEN1ALDH1A1 | |
| SCHEMBL9429006 | 0.86 | HRH1 (0.60) | HRH1HRH2DRD2DRD3HTR1A | |
| SCHEMBL9429616 | 0.86 | HRH3 (0.58) | HRH1HRH2DRD2HRH3MEN1 | |
| SCHEMBL9428476 | 0.84 | ALDH1A1 (0.58) | HRH1HRH2DRD2DRD3HTR1A | |
| SCHEMBL9428742 | 0.84 | HRH1 (0.47) | HRH1HRH2DRD2DRD3HTR1A | |
| SCHEMBL9428306 | 0.84 | LMNA (0.59) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL9428590 | 0.84 | DRD2 (0.48) | HRH1HRH2DRD2DRD3HTR1A | |
| SCHEMBL9429765 | 0.83 | HRH3 (0.52) | HRH1DRD2HTR1AHTR2AHRH3 | |
| Hydrochloric Acid SCHEMBL9428802 | 0.83 | KMT2A (0.58) | HRH1HTR2CDRD2DRD3HTR2A | |
| SCHEMBL9429583 | 0.82 | MEN1 (0.44) | HRH1CCR3HRH2DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |