Sugi Predict

Sugi Predict / Compounds / SCHEMBL942973

SCHEMBL942973

SCHEMBL942973

FC(F)(F)c1cccc(S)c1C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 1/20 0.41
▸ P2RX7 Q99572 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.35
▸ POLB P06746 2/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ AXL P30530 1/20 0.35
▸ KIF11 P52732 1/20 0.35
▸ CES1 P23141 1/20 0.34
▸ IDO1 P14902 3/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CNR2 P34972 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ TDO2 P48775 1/20 0.33
▸ LMNA P02545 2/20 0.32
▸ PNMT P11086 1/20 0.32
▸ CHRNB2 P17787 1/20 0.32
▸ CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2000756 0.84 HSD11B1 (0.46) HSD11B1P2RX7ALDH1A1POLBTDP1
Lithium SCHEMBL5691154 0.81 HSD11B1 (0.44) HSD11B1P2RX7ALDH1A1POLBTDP1
SCHEMBL6067687 0.77 HSD11B1 (0.55) HSD11B1P2RX7ALDH1A1POLBTDP1
SCHEMBL29427756 0.76 ALDH1A1 (0.44) HSD11B1P2RX7ALDH1A1POLBTDP1
SCHEMBL1815828 0.76 ALDH1A1 (0.39) HSD11B1P2RX7ALDH1A1POLBTDP1
SCHEMBL72183 0.76 ALDH1A1 (0.44) HSD11B1P2RX7ALDH1A1POLBTDP1
SCHEMBL14932033 0.75 HSD11B1 (0.41) HSD11B1P2RX7ALDH1A1POLBTDP1
SCHEMBL28918929 0.75 IDO1 (0.43) HSD11B1P2RX7ALDH1A1POLBTDP1
SCHEMBL7602903 0.75 HSD11B1 (0.41) HSD11B1P2RX7ALDH1A1POLBTDP1
SCHEMBL27956349 0.75 TRPA1 (0.36) P2RX7ALDH1A1CES1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110192294-A LITHIUM ELECTRODE AND LITHIUM SECONDARY BATTERY COMPRISING SAME 株式会社LG化学 2019-08-30 — — CN claimed
CN-118420589-A Near infrared fluorescent probe with large Stokes shift for detecting Cys, and preparation and application thereof 嘉兴学院 2024-08-02 — — CN disclosed
CN-110471257-A The manufacturing method of photosensitive polymer combination, photosensitive dry film and its manufacturing method, resist film, substrate and plating forming object TOKYO OHKA KOGYO COMPANY 2019-11-19 — — CN disclosed
CN-110192294-A LITHIUM ELECTRODE AND LITHIUM SECONDARY BATTERY COMPRISING SAME 株式会社LG化学 2019-08-30 — — CN disclosed
CN-105542049-B Preparation method of the side arm with the cis- 1,4 conjugated diene hydrocarbon polymer of height of double bond or side arm with function 中国科学院长春应用化学研究所 2018-08-07 — — CN disclosed
US-8987516-B2 Process for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2015-03-24 — — US disclosed
EP-2468722-B1 Process for producing arylsulfur halotetrafluorides UBE INDUSTRIES (JP) 2014-10-01 — — EP disclosed
EP-2468721-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2014-02-26 — — EP disclosed
EP-2468720-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-11-27 — — EP disclosed
EP-2468719-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-10-16 — — EP disclosed
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-05-27 — — US disclosed
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-03-25 — — US disclosed
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-02-04 — — US disclosed
WO-2010014665-A1 METHODS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2010-02-04 — — WO disclosed
EP-2137144-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T Research, Inc. (US) 2009-12-30 — — EP disclosed
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2009-11-19 — — US disclosed
US-7592491-B2 Process for producing arylsulfur pentafluorides IM&T RESEARCH, INC. (US) 2009-09-22 — — US disclosed
WO-2008118787-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM & T RESEARCH, INC. (US) 2008-10-02 — — WO disclosed
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2008-09-25 — — US disclosed
EP-0365397-A2 Beta-D-phenyl thioxylosides, method for their preparation and their use in therapy FOURNIER INDUSTRIE ET SANTE (FR) 1990-04-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA HSD11B1 1564/4885P2RX7 2554/4885ALDH1A1 2190/4885
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides BRPF1, SFXN3, SLFN12 HSD11B1 3634/4885P2RX7 1717/4885ALDH1A1 3759/4885
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA HSD11B1 1564/4885P2RX7 2554/4885ALDH1A1 2190/4885
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES PFAS, MPST, ARSA HSD11B1 1564/4885P2RX7 2554/4885ALDH1A1 2190/4885
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA HSD11B1 1564/4885P2RX7 2554/4885ALDH1A1 2190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.