Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385515 | 0.87 | ALDH1A1 (0.47) | DRD2DRD3DRD1HTR1AMAPT | |
| Oxalic Acid SCHEMBL9388883 | 0.86 | ALDH1A1 (0.46) | DRD2DRD3HTR1AMAPTKDM4E | |
| SCHEMBL9428545 | 0.83 | HTR1A (0.56) | DRD2DRD3HTR1AKDM4EALDH1A1 | |
| SCHEMBL9429079 | 0.77 | DRD2 (0.47) | DRD2DRD3DRD1HTR1AMAPT | |
| SCHEMBL9429332 | 0.74 | DRD2 (0.53) | DRD2DRD3DRD1HTR1AHRH3 | |
| SCHEMBL9870181 | 0.74 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1PKM | |
| SCHEMBL9429031 | 0.74 | HTR1A (0.55) | DRD2DRD3HTR1AMAPT | |
| SCHEMBL9429626 | 0.74 | HTR1A (0.51) | DRD2DRD3HTR1AKDM4EALDH1A1 | |
| SCHEMBL29508119 | 0.74 | DRD2 (0.69) | DRD2DRD3DRD1HTR1AMAPT | |
| Hydrochloric Acid SCHEMBL9429549 | 0.73 | HTR1A (0.54) | DRD2DRD3HTR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |