Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394406 | 0.73 | RAB9A (0.62) | ATMTHRBRECQLNPSR1TDP1 | |
| SCHEMBL10841737 | 0.70 | THRB (0.61) | ATMTHRBRECQLNPSR1TDP1 | |
| SCHEMBL12360611 | 0.70 | TSHR (0.78) | KEAP1NFE2L2KMT2ATSHRACHE | |
| SCHEMBL4429016 | 0.70 | KEAP1 (0.53) | ATMTHRBRECQLNPSR1TDP1 | |
| SCHEMBL6738366 | 0.69 | TSHR (0.76) | TDP1KMT2APOLBTSHRACHE | |
| SCHEMBL1544856 | 0.68 | CFTR (0.50) | ATMTHRBRECQLNPSR1TDP1 | |
| SCHEMBL11385077 | 0.68 | KEAP1 (0.52) | ATMTHRBRECQLNPSR1TDP1 | |
| SCHEMBL25440198 | 0.68 | CYP1A2 (0.55) | ATMTHRBRECQLNPSR1TDP1 | |
| SCHEMBL10391024 | 0.68 | L3MBTL1 (0.59) | TDP1KEAP1NFE2L2CDC7MAP4K4 | |
| SCHEMBL22347556 | 0.68 | ALDH1A1 (0.54) | ATMTHRBRECQLNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336780-A | 5-amino-1-hydroximoyl pyrazoles | AGFA GEVAERT AKTIENGESELLSCHAFT (DE) | 1994-08-09 | — | — | US | disclosed |