Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10842650 | 0.92 | NPSR1 (0.53) | THRBTDP1RECQLNPSR1ATM | |
| SCHEMBL10841715 | 0.87 | THRB (0.45) | THRBTDP1RECQLNPSR1ATM | |
| SCHEMBL10842466 | 0.83 | MEN1 (0.47) | THRBTDP1RECQLNPSR1MAPT | |
| SCHEMBL10842636 | 0.81 | POLB (0.51) | THRBTDP1RECQLNPSR1ATM | |
| SCHEMBL11849955 | 0.74 | L3MBTL1 (0.50) | THRBTDP1RECQLNPSR1POLB | |
| SCHEMBL10843797 | 0.74 | ALDH1A1 (0.40) | THRBTDP1RECQLNPSR1POLB | |
| SCHEMBL9429899 | 0.70 | ATM (0.56) | THRBTDP1RECQLNPSR1ATM | |
| SCHEMBL18394406 | 0.69 | RAB9A (0.62) | THRBTDP1RECQLNPSR1ATM | |
| SCHEMBL16435341 | 0.68 | TSHR (0.58) | THRBTDP1MAPTALDH1A1KMT2A | |
| SCHEMBL10842673 | 0.68 | MAPT (0.45) | THRBTDP1RECQLNPSR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |