Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321094 | 0.82 | GABRA1 (0.48) | HTTPOLB | |
| SCHEMBL9404342 | 0.80 | ALDH1A1 (0.40) | ALOX15CYP1A2CYP3A4USP2CYP2D6 | |
| SCHEMBL7321007 | 0.75 | HTR4 (0.43) | CYP1A2CYP3A4CYP2D6HTTPOLB | |
| SCHEMBL9404311 | 0.72 | GABRA1 (0.48) | — | |
| SCHEMBL9404376 | 0.72 | HTT (0.58) | ALOX15TSHRHTTPOLBKDM4E | |
| SCHEMBL7327105 | 0.71 | GABRA1 (0.47) | — | |
| SCHEMBL9404284 | 0.70 | RXFP1 (0.49) | ALOX15CYP1A2CYP2C19HTTPOLB | |
| SCHEMBL9404286 | 0.69 | GABRA1 (0.48) | — | |
| SCHEMBL9404296 | 0.69 | HTT (0.44) | ALOX15HTTPOLBKDM4EMAPT | |
| SCHEMBL9404490 | 0.67 | OPRK1 (0.35) | ALOX15CYP1A2CYP3A4USP2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371080-A | Central nervous system disorders | NOVO NORDISK A/S | 1994-12-06 | — | — | US | disclosed |