Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433920 | 0.79 | TBXAS1 (0.56) | NAPRTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9434718 | 0.79 | NAPRT (0.50) | NAPRTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9434498 | 0.78 | NAPRT (0.49) | NAPRTKMT2AHTTCYP1A2CYP3A4 | |
| SCHEMBL9433799 | 0.78 | MAPT (0.61) | NAPRTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9433617 | 0.78 | HSD11B1 (0.50) | NAPRTNPC1RAB9AKMT2ACYP1A2 | |
| SCHEMBL9433573 | 0.78 | NAPRT (0.49) | NAPRTNPC1RAB9AKMT2ACYP1A2 | |
| SCHEMBL9433826 | 0.77 | TBXAS1 (0.57) | NAPRTNPC1RAB9AKMT2AHTT | |
| SCHEMBL9434219 | 0.77 | ALDH1A1 (0.49) | NAPRTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9434333 | 0.77 | RAB9A (0.60) | NAPRTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9433602 | 0.77 | NAPRT (0.44) | NAPRTCYP1A2CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |