Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192267 | 0.83 | ENPP3 (0.42) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31194860 | 0.82 | MAPK13 (0.57) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL472566 | 0.81 | NPC1 (0.37) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1617773 | 0.80 | ACHE (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL21051602 | 0.80 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK13 | |
| SCHEMBL5546174 | 0.80 | CCR9 (0.44) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5545503 | 0.80 | PTGS2 (0.54) | NPC1TSHRRAB9ASMN1; SMN2MAPK13 | |
| SCHEMBL342242 | 0.79 | MAPK13 (0.58) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29154643 | 0.77 | MAPK13 (0.69) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8192595 | 0.76 | LMNA (0.43) | MAPK13MAPK12MAPK11MAPK14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994015920-A1 | BENZANILIDE DERIVATIVES AS 5-HT1D-ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1994-07-21 | — | — | WO | disclosed |