Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 4/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PPIA | P62937 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434738 | 0.84 | SLC1A5 (0.46) | SLC1A5HTR1ADRD2TACR1MEN1 | |
| SCHEMBL5793302 | 0.75 | TACR1 (0.46) | SLC1A5HTR1ADRD2TACR1PTPN1 | |
| SCHEMBL16899929 | 0.72 | SMN1; SMN2 (0.57) | KDM4EMEN1KMT2A | |
| SCHEMBL23673331 | 0.69 | ALDH1A1 (0.53) | TACR1KDM4EKMT2APTPN1 | |
| SCHEMBL8537757 | 0.69 | TACR1 (0.60) | TACR1 | |
| SCHEMBL30064008 | 0.67 | L3MBTL1 (0.49) | TACR1 | |
| SCHEMBL23683173 | 0.66 | LMNA (0.63) | TACR1KDM4EMEN1KMT2A | |
| SCHEMBL27312591 | 0.65 | TACR1 (0.52) | TACR1KDM4EMEN1KMT2A | |
| SCHEMBL8507790 | 0.65 | TACR1 (0.49) | TACR1PTGER1 | |
| SCHEMBL10127312 | 0.64 | SMN1; SMN2 (0.50) | KDM4ETSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002461-A1 | AZACYCLIC COMPOUNDS | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-03 | — | — | WO | claimed |