Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435408 | 0.84 | SLC1A5 (0.43) | SLC1A5HTR1ADRD2MEN1KMT2A | |
| SCHEMBL5793302 | 0.73 | TACR1 (0.46) | SLC1A5HTR1ADRD2POLBTACR1 | |
| SCHEMBL9006032 | 0.72 | TACR1 (0.54) | TACR1 | |
| SCHEMBL23673331 | 0.68 | ALDH1A1 (0.53) | ALDH1A1POLBKMT2AHTTTACR1 | |
| SCHEMBL23683173 | 0.67 | LMNA (0.63) | ALDH1A1MEN1KMT2AHTTTACR1 | |
| SCHEMBL18002137 | 0.66 | PTPN1 (0.45) | ALDH1A1POLBLRRK2GRM2PTPN1 | |
| SCHEMBL28034152 | 0.65 | CHRNB2 (0.43) | ALDH1A1POLBGPBAR1TACR1 | |
| SCHEMBL7382021 | 0.65 | CACNA1H (0.45) | POLBMEN1KMT2AGPBAR1 | |
| SCHEMBL8501851 | 0.64 | HTR1A (0.57) | SLC1A5HTR1ADRD2ALDH1A1POLB | |
| SCHEMBL17551821 | 0.64 | LRRK2 (0.77) | LRRK2SRPK3SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002461-A1 | AZACYCLIC COMPOUNDS | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-03 | — | — | WO | claimed |