Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 6/20 | 0.35 |
| ▸ | NOS2 | P35228 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289312 | 0.70 | ACHE (0.44) | TDP1ALDH1A1GLAGPR84TP53 | |
| SCHEMBL7078686 | 0.69 | TDP1 (0.48) | TDP1ALDH1A1GLATP53CYP3A4 | |
| SCHEMBL11665066 | 0.67 | NOS3 (0.37) | NOS3NOS2SMN1; SMN2 | |
| SCHEMBL11742766 | 0.65 | NOS3 (0.62) | NOS3NOS2TSHRSMN1; SMN2 | |
| SCHEMBL9095681 | 0.65 | NOS3 (0.41) | NOS3NOS2TSHR | |
| Fluorene SCHEMBL3914798 | 0.65 | ALDH1A1 (0.45) | TDP1ALDH1A1GLATP53CYP3A4 | |
| Fluorene SCHEMBL154228 | 0.64 | TDP1 (0.47) | TDP1ALDH1A1GLATP53CYP3A4 | |
| SCHEMBL394006 | 0.64 | TDP1 (0.47) | TDP1ALDH1A1GLATP53CYP3A4 | |
| Fluorene SCHEMBL919560 | 0.64 | TDP1 (0.44) | TDP1ALDH1A1GLATP53CYP3A4 | |
| Fluorene SCHEMBL28987665 | 0.63 | ALDH1A1 (0.40) | TDP1ALDH1A1GLASMN1; SMN2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022846-A1 | COMPOUNDS ENHANCING ANTITUMOR ACTIVITY OF OTHER CYTOTOXIC AGENTS | PFIZER INC. (US) | 1994-10-13 | — | — | WO | disclosed |