SCHEMBL94367

SCHEMBL94367

C[C@]12C=CC(=O)C=C1CC[C@H]1[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@]12F

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.79
CYP3A4 P08684 7/20 0.79
LMNA P02545 5/20 0.79
ALDH1A1 P00352 1/20 0.79
NR3C1 P04150 7/20 0.73
HSD17B10 Q99714 4/20 0.73
PGR P06401 4/20 0.73
NFKB1 P19838 3/20 0.73
CYP2C9 P11712 2/20 0.73
PMP22 Q01453 2/20 0.73
CYP2J2 P51589 1/20 0.73
BLM P54132 1/20 0.73
CYP2C19 P33261 1/20 0.73
TSHR P16473 2/20 0.71
AR P10275 2/20 0.71
MEN1 O00255 1/20 0.71
CYP2D6 P10635 1/20 0.71
KMT2A Q03164 1/20 0.71
APEX1 P27695 1/20 0.71
NPSR1 Q6W5P4 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9654452 1.00 HIF1A (0.79) HIF1ACYP3A4LMNAALDH1A1NR3C1
SCHEMBL17884670 1.00 HIF1A (0.79) HIF1ACYP3A4LMNAALDH1A1NR3C1
SCHEMBL13657566 1.00 HIF1A (0.79) HIF1ACYP3A4LMNAALDH1A1NR3C1
SCHEMBL17665286 1.00 HIF1A (0.79) HIF1ACYP3A4LMNAALDH1A1NR3C1
SCHEMBL3764416 1.00 HIF1A (0.79) HIF1ACYP3A4LMNAALDH1A1NR3C1
SCHEMBL19715951 1.00 HIF1A (0.79) HIF1ACYP3A4LMNAALDH1A1NR3C1
SCHEMBL1122877 1.00 HIF1A (0.79) HIF1ACYP3A4LMNAALDH1A1NR3C1
SCHEMBL11856116 0.92 HIF1A (0.79) HIF1ACYP3A4LMNAALDH1A1NR3C1
SCHEMBL11856120 0.92 HIF1A (0.79) HIF1ACYP3A4LMNAALDH1A1NR3C1
SCHEMBL11845795 0.91 CYP3A4 (0.77) HIF1ACYP3A4LMNAALDH1A1NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1489 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12529704-B2 Methods for objective assessment of stress, early detection of risk for stress disorders, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2026-01-20 US claimed
EP-4178579-B1 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE AS GLUCOCORTICOID-SPARING AGENT METRIOPHARM AG (CH) 2025-02-12 EP claimed
US-20240374734-A1 Immunomodulatory Combinations of Antigen and Drug-Lipid Conjugate INTEGRATED NANOTHERAPEUTICS INC. (CA) 2024-11-14 US claimed
WO-2024189434-A1 USE OF NADOLOL TO TREAT PULMONARY SYMPTOMS ASSOCIATED WITH INFECTIONS WITH SARS-CoV-2 CHRONIC AIRWAY THERAPEUTICS LIMITED (AU) 2024-09-19 WO claimed
EP-4398930-A1 IMMUNOMODULATORY COMBINATIONS OF ANTIGEN AND DRUG-LIPID CONJUGATE Integrated Nanotherapeutics Inc. (CA) 2024-07-17 EP claimed
US-20240165130-A1 COMPOSITE DRUG PARTICLES AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-05-23 US claimed
EP-4312991-A1 COMPOSITE DRUG PARTICLES AND USES THEREOF The Regents Of The University Of Michigan (US) 2024-02-07 EP claimed
US-20230420110-A1 METHODS FOR OBJECTIVE ASSESSMENT, RISK PREDICTION, MATCHING TO EXISTING MEDICATIONS AND NEW METHODS OF USING DRUGS, AND MONITORING RESPONSES TO TREATMENTS FOR MOOD DISORDERS UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2023-12-28 US claimed
EP-4247259-A1 METHODS FOR OBJECTIVE ASSESSMENT, RISK PREDICTION, MATCHING TO EXISTING MEDICATIONS AND NEW METHODS OF USING DRUGS, AND MONITORING RESPONSES TO TREATMENTS FOR MOOD DISORDERS Indiana University Research and Technology Corporation (US) 2023-09-27 EP claimed
US-20230241060-A1 GLUCOCORTICOID-SPARING AGENT METRIOPHARM AG (CH) 2023-08-03 US claimed
WO-2001015744-A9 SYSTEMIC INFLAMMATORY MARKERS AS DIAGNOSTIC TOOLS IN THE PREVENTION OF ATHEROSCLEROTIC DISEASES BRIGHAM & WOMENS HOSPITAL (US) 2002-09-26 WO claimed
EP-1212101-A1 SYSTEMIC INFLAMMATORY MARKERS AS DIAGNOSTIC TOOLS IN THE PREVENTION OF ATHEROSCLEROTIC DISEASES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2002-06-12 EP claimed
US-20020064524-A1 Formulation for topical non-invasive application in vivo IDEA AG (DE) 2002-05-30 US claimed
EP-1140021-A1 IMPROVED FORMULATION FOR TOPICAL NON-INVASIVE APPLICATION IN VIVO IDEA AG (DE) 2001-10-10 EP claimed
WO-2001015744-A1 SYSTEMIC INFLAMMATORY MARKERS AS DIAGNOSTIC TOOLS IN THE PREVENTION OF ATHEROSCLEROTIC DISEASES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2001-03-08 WO claimed
EP-1049471-A1 COMPOSITIONS AND METHODS FOR TREATING ATOPIC DERMATITIS, ANGIOEDEMA AND OTHER DISORDERS USING ANTIHISTAMINES AND GLUCOCORTICOIDS SCHERING CORPORATION (US) 2000-11-08 EP claimed
WO-2000051605-A1 COMPOSITIONS AND METHODS FOR TREATING ATOPIC DERMATITIS, ANGIOEDEMA AND OTHER DISORDERS USING ANTIHISTAMINES AND GLUCOCORTICOIDS SCHERING CORPORATION (US) 2000-09-08 WO claimed
WO-2000038653-A1 IMPROVED FORMULATION FOR TOPICAL NON-INVASIVE APPLICATION IN VIVO IDEA AG. (DE) 2000-07-06 WO claimed
EP-0186948-B1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 17ALPHA-HYDROXYPROGESTERONES AND CORTICOIDS FROM AN ENOL STEROID THE UPJOHN COMPANY (US) 1989-01-25 EP claimed
EP-0186948-A1 Process and intermediates for the preparation of 17alpha-hydroxyprogesterones and corticoids from an enol steroid THE UPJOHN COMPANY (US) 1986-07-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240165130-A1 COMPOSITE DRUG PARTICLES AND USES THEREOF LIPC, LIPA, FABP4 HIF1A 4001/4885CYP3A4 193/4885LMNA 839/4885
US-12529704-B2 Methods for objective assessment of stress, early detection of risk for stress disorders, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs DDB1, DDX6, DDX21 HIF1A 2088/4885CYP3A4 1221/4885LMNA 1608/4885
US-20020064524-A1 Formulation for topical non-invasive application in vivo CUTA, LPO, GPX4 HIF1A 2297/4885CYP3A4 1398/4885LMNA 3910/4885
US-20240374734-A1 Immunomodulatory Combinations of Antigen and Drug-Lipid Conjugate LY96, CD74, TLR9 HIF1A 3228/4885CYP3A4 4520/4885LMNA 2079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.