Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437644 | 0.89 | LMNA (0.41) | RENCTSSTSHRGAACYP2C19 | |
| SCHEMBL9437584 | 0.87 | CTSS (0.34) | RENCTSSTSHRGAACYP2C19 | |
| SCHEMBL7338169 | 0.80 | HSD17B10 (0.50) | CTSSHSD17B10CHRM1TSHRGAA | |
| SCHEMBL7330813 | 0.80 | HSD17B10 (0.50) | CTSSHSD17B10CHRM1TSHRGAA | |
| SCHEMBL7333712 | 0.78 | REN (0.41) | RENCTSSHSD17B10CHRM1TSHR | |
| SCHEMBL7325021 | 0.78 | REN (0.41) | RENCTSSHSD17B10CHRM1TSHR | |
| SCHEMBL7332863 | 0.74 | HSD17B10 (0.46) | RENCTSSHSD17B10CHRM1TSHR | |
| SCHEMBL9437563 | 0.72 | CHRM1 (0.42) | RENCTSSHSD17B10CHRM1TSHR | |
| SCHEMBL7353235 | 0.71 | REN (0.47) | RENCTSSHSD17B10 | |
| SCHEMBL7378656 | 0.70 | REN (0.38) | RENCTSSHSD17B10CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |