Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437637 | 0.96 | ALDH1A1 (0.40) | ALDH1A1CTSBHSD17B10MEN1KMT2A | |
| SCHEMBL9437535 | 0.89 | REN (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2REN | |
| SCHEMBL9437597 | 0.88 | MEN1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2REN | |
| SCHEMBL9437653 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL9437538 | 0.84 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL7332174 | 0.82 | MMP2 (0.51) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL7332179 | 0.82 | MMP2 (0.51) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL9437534 | 0.80 | HSD17B10 (0.38) | ALDH1A1CTSBHSD17B10CHRM1CTSL | |
| SCHEMBL9437610 | 0.78 | HSD17B10 (0.38) | ALDH1A1CTSBHSD17B10MEN1KMT2A | |
| SCHEMBL9437628 | 0.77 | AVPR1B (0.40) | ALDH1A1CTSBHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |