SCHEMBL944245

SCHEMBL944245

C=CCc1cc(COC(C)=O)cc(CC=C)c1O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
CYP3A4 P08684 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPK1 P28482 1/20 0.40
ALOX5 P09917 2/20 0.40
PTGS1 P23219 1/20 0.39
DHFR P00374 1/20 0.37
GABRA1 P14867 4/20 0.37
GABRB2 P47870 4/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
GABRA2 P47869 1/20 0.37
IDH1 O75874 1/20 0.36
MET P08581 1/20 0.35
AKR1B10 O60218 1/20 0.35
MMP2 P08253 1/20 0.35
AKR1B1 P15121 1/20 0.35
AKR1C3 P42330 1/20 0.35
PAK1 Q13153 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7566203 0.83 ALDH1A1 (0.52) ALDH1A1CYP3A4KDM4EIDH1MET
SCHEMBL944103 0.80 KDM4E (0.42) ALDH1A1CYP3A4KDM4EALOX5PTGS1
Acetic Acid SCHEMBL9331113 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4KDM4EIDH1MET
SCHEMBL3259424 0.79 GABRA1 (0.41) ALDH1A1CYP3A4KDM4EMAPK1ALOX5
SCHEMBL9307833 0.78 HTT (0.45) ALDH1A1KDM4EDHFRGABRA1GABRB2
SCHEMBL9403272 0.75 GABRA1 (0.38) ALDH1A1KDM4EMAPK1ALOX5DHFR
SCHEMBL2461750 0.74 XDH (0.48) ALDH1A1CYP3A4KDM4EALOX5PTGS1
SCHEMBL8367993 0.74 ALDH1A1 (0.43) ALDH1A1CYP3A4ALOX5
SCHEMBL7042257 0.74 HSP90AB1 (0.54) ALDH1A1CYP3A4KDM4EMAPK1ALOX5
SCHEMBL5666942 0.74 ALDH1A1 (0.64) ALDH1A1CYP3A4KDM4EIDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8766016-B2 Green and atom-economical processes for producing phenolic antioxidants ALBERMARLE CORPORATION (US) 2014-07-01 US disclosed
US-20120108854-A1 GREEN AND ATOM-ECONOMICAL PROCESSES FOR PRODUCING PHENOLIC ANTIOXIDANTS ALBEMARLE CORPORATION (US) 2012-05-03 US disclosed
WO-2011005735-A1 GREEN AND ATOM-ECONOMICAL PROCESSES FOR PRODUCING PHENOLIC ANTIOXIDANTS ALBEMARLE CORPORATION (US) 2011-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108854-A1 GREEN AND ATOM-ECONOMICAL PROCESSES FOR PRODUCING PHENOLIC ANTIOXIDANTS TYR, TXN2, TFEB ALDH1A1 246/4885CYP3A4 692/4885KDM4E 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.