SCHEMBL944441

SCHEMBL944441

Brc1cccc(SSc2cccc(Br)c2Br)c1Br

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APOBEC3G Q9HC16 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HTR7 P34969 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30802271 1.00 APOBEC3G (0.36) APOBEC3GMEN1MAPTKMT2ANPSR1
SCHEMBL29661845 0.83 LMNA (0.39) HTR7MAOAMAOBALDH1A1LMNA
SCHEMBL8420683 0.83 LMNA (0.39) HTR7MAOAMAOBALDH1A1LMNA
SCHEMBL951192 0.79 HTR7 (0.31) HTR7MAOAMAOB
SCHEMBL28029391 0.79 HTR7 (0.35) MEN1MAPTKMT2AHTR7MAOA
SCHEMBL31412108 0.77 APOBEC3G (0.46) APOBEC3GMEN1MAPTKMT2ANPSR1
SCHEMBL224791 0.77 APOBEC3G (0.46) APOBEC3GMEN1MAPTKMT2ANPSR1
SCHEMBL355898 0.75
SCHEMBL1814655 0.74 TDP1 (0.31)
SCHEMBL943477 0.74 APOBEC3G (0.33) APOBEC3GMEN1MAPTKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987516-B2 Process for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2015-03-24 US disclosed
US-8907020-B2 Golf ball SRI SPORTS LIMITED (JP) 2014-12-09 US disclosed
US-8877869-B2 Method for selecting organic sulfur compound for golf ball, method for producing golf ball, and golf ball SRI SPORTS LIMITED (JP) 2014-11-04 US disclosed
EP-2468722-B1 Process for producing arylsulfur halotetrafluorides UBE INDUSTRIES (JP) 2014-10-01 EP disclosed
EP-2468721-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2014-02-26 EP disclosed
EP-2468720-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-11-27 EP disclosed
US-8592526-B2 Golf ball SRI SPORTS LIMITED (JP) 2013-11-26 US disclosed
EP-2468719-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-10-16 EP disclosed
US-8399720-B2 Methods for producing fluorinated phenylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2013-03-19 US disclosed
EP-2468721-A1 Process for producing arylsulfur pentafluorides UBE Industries, Ltd. (JP) 2012-06-27 EP disclosed
EP-1863785-A1 NOVEL THIOPHENE SULFOXIMINES FOR TREATING CMPLEMENT-MEDIATED DESEASES AND CONDITIONS JANSSEN PHARMACEUTICA N.V. (BE) 2007-12-12 EP disclosed
US-20070066667-A1 Novel thiophene sulfoximines, compositions thereof, and methods treating complement-mediated diseases and conditions JANSSEN PHARMACEUTICA N.V. (BE) 2007-03-22 US disclosed
US-7125346-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2006-10-24 US disclosed
WO-2006101860-A1 NOVEL THIOPHENE SULFOXIMINES FOR TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS JANSSEN PHARMACEUTICA N.V. (BE) 2006-09-28 WO disclosed
US-20050202902-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. 2005-09-15 US disclosed
US-6838524-B2 Solid golf ball SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2005-01-04 US disclosed
US-6646165-B2 Reacting halothiophenol compound with an alkali metal hydroxide to obtain an alkali metal halothiophenolate compound; oxidizing in the presence of a mineral acid to produce bishalophenyl disulfide SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2003-11-11 US disclosed
US-20030060665-A1 Process for producing bishalophenyl disulfide SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2003-03-27 US disclosed
US-20030032501-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-02-13 US disclosed
EP-1277731-A1 PROCESS FOR PRODUCING BISHALOPHENYL DISULFIDE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2003-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066667-A1 Novel thiophene sulfoximines, compositions thereof, and methods treating complement-mediated diseases and conditions C5, C1QBP, C1R APOBEC3G 4591/4885MEN1 2090/4885MAPT 4246/4885
US-20030060665-A1 Process for producing bishalophenyl disulfide MPST, TST, GRHPR APOBEC3G 4272/4885MEN1 2913/4885MAPT 2177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.