Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446002 | 1.00 | MAPT (0.39) | MAPTL3MBTL1EGFRTSHRALDH1A1 | |
| SCHEMBL9445912 | 0.80 | MEN1 (0.48) | MAPTL3MBTL1ALDH1A1SCN9A | |
| SCHEMBL9445914 | 0.80 | MEN1 (0.48) | MAPTL3MBTL1ALDH1A1SCN9A | |
| SCHEMBL702504 | 0.77 | NPSR1 (0.47) | MAPTEGFRTSHRKDM4EHPGD | |
| SCHEMBL9445924 | 0.76 | TSHR (0.46) | MAPTEGFRTSHRALDH1A1KDM4E | |
| SCHEMBL9448847 | 0.76 | MAPT (0.43) | MAPTEGFRSMN1; SMN2MAPK1HTT | |
| SCHEMBL9445932 | 0.73 | NPSR1 (0.41) | MAPTEGFRTSHRKDM4EHPGD | |
| SCHEMBL10348806 | 0.72 | KMT2A (0.45) | MAPTEGFRTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL914622 | 0.72 | ALDH1A1 (0.51) | EGFRTSHRALDH1A1KDM4EHTT | |
| SCHEMBL23257604 | 0.71 | MAPT (0.43) | MAPTL3MBTL1TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |