Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51510 | 0.91 | ESR1 (0.49) | KIF11ESR1ESR2KMT2ATAAR1 | |
| SCHEMBL56267 | 0.87 | ATM (0.53) | KIF11ATMESR1ESR2SLC6A2 | |
| SCHEMBL28689681 | 0.85 | ACHE (0.46) | MEN1KMT2ATAAR1CYP2C19CYP1A2 | |
| SCHEMBL27708349 | 0.83 | ESR1 (0.42) | KIF11ESR1ESR2TAAR1CYP1A2 | |
| SCHEMBL9447544 | 0.81 | ALDH1A1 (0.48) | KIF11ATMESR1ESR2SLC6A2 | |
| SCHEMBL10625675 | 0.80 | ATM (0.47) | ATMSLC6A2TAAR1EBPSIGMAR1 | |
| SCHEMBL28680251 | 0.76 | CYP1A2 (0.46) | ATMMEN1KMT2ATAAR1SIGMAR1 | |
| SCHEMBL6985798 | 0.74 | KIF11 (0.51) | KIF11ATMMEN1KMT2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL10926313 | 0.74 | SIGMAR1 (0.49) | ATMTAAR1EBPSIGMAR1 | |
| SCHEMBL29078985 | 0.72 | MEN1 (0.40) | KIF11ATMMEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274104-A | N-substituted heterocyclic derivatives useful in the treatment of cardiovascular disorders | ELF SANOFI, A FRENCH CORP. (FR) | 1993-12-28 | — | — | US | disclosed |