Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448538 | 0.83 | EPAS1 (0.31) | EPAS1CCR2ALDH1A1 | |
| SCHEMBL9448437 | 0.81 | L3MBTL1 (0.34) | CCR2 | |
| SCHEMBL22090249 | 0.77 | EPAS1 (0.36) | EPAS1ALDH1A1HPGD | |
| SCHEMBL9078012 | 0.77 | LMNA (0.39) | EPAS1ALDH1A1HPGD | |
| SCHEMBL9075730 | 0.76 | VCAM1 (0.38) | EPAS1ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL9448525 | 0.75 | CCR2 (0.40) | EPAS1CCR2ALDH1A1 | |
| SCHEMBL3118107 | 0.75 | CCR2 (0.38) | EPAS1CCR2ALDH1A1HPGD | |
| SCHEMBL7976409 | 0.74 | ALDH1A1 (0.35) | CCR2ALDH1A1KDM4E | |
| SCHEMBL31001623 | 0.72 | CCR2 (0.38) | EPAS1CCR2HPGDPTGS2 | |
| SCHEMBL8176124 | 0.72 | CCR2 (0.38) | EPAS1CCR2HPGDPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34423-E | For producing 4-benzoyl-5-hydroxypyrazoles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| US-RE34408-E | Reacting carbon monoxide with a 5-hydroxy pyrazole and a substituted benzene | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0344775-B1 | PROCESS FOR PRODUCING 4-BENZOYL-5-HYDROXYPYRAZOLES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5087724-A | For herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| US-4942246-A | CARBONYLATION, CONDENSATION, HERBICIDES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-07-17 | — | — | US | disclosed |
| EP-0344775-A1 | Process for producing 4-benzoyl-5-hydroxypyrazoles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-12-06 | — | — | EP | disclosed |