Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448767 | 0.90 | MCHR1 (0.50) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL9449042 | 0.86 | HPGD (0.35) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL9448864 | 0.85 | GAA (0.47) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL9449116 | 0.85 | KMT2A (0.41) | ALDH1A1KMT2AGAATSHRHTT | |
| SCHEMBL9448852 | 0.84 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL9449197 | 0.82 | CTSV (0.47) | KDM4EHSD17B10HPGDMAPTHTT | |
| SCHEMBL9449046 | 0.82 | KMT2A (0.36) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL9448924 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL9449289 | 0.82 | KMT2A (0.38) | KDM4EALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL9448855 | 0.80 | CHRNA7 (0.49) | GAAHTR2AHTR2CCHRNA7MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227386-A | INDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-07-13 | — | — | US | disclosed |