Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449046 | 0.93 | KMT2A (0.36) | KMT2AGAAKDM4EALDH1A1GLA | |
| SCHEMBL9448900 | 0.92 | MAPKAPK2 (0.40) | KMT2AGAAKDM4EALDH1A1GLA | |
| SCHEMBL9448864 | 0.88 | GAA (0.47) | KMT2AGAAKDM4EALDH1A1GLA | |
| SCHEMBL9449086 | 0.85 | GABRA1 (0.41) | KMT2AGAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL9448869 | 0.85 | MAPKAPK2 (0.41) | KMT2AGAAKDM4EALDH1A1PDGFRB | |
| SCHEMBL9449052 | 0.82 | KDM4E (0.43) | KMT2AGAAKDM4EALDH1A1GLA | |
| SCHEMBL9449042 | 0.80 | HPGD (0.35) | GAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9449097 | 0.79 | LMNA (0.40) | GAAKDM4EALDH1A1GLASMN1; SMN2 | |
| SCHEMBL9449116 | 0.79 | KMT2A (0.41) | KMT2AGAAALDH1A1TSHRHTT | |
| SCHEMBL9448924 | 0.77 | KDM4E (0.40) | KMT2AGAAKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227386-A | INDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-07-13 | — | — | US | disclosed |