Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449189 | 0.91 | MCHR1 (0.40) | HPGDKDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9449052 | 0.86 | KDM4E (0.43) | HPGDKDM4EALDH1A1GAACYP1A2 | |
| SCHEMBL9448864 | 0.83 | GAA (0.47) | KDM4EALDH1A1GAACYP2D6CHRM2 | |
| SCHEMBL9449046 | 0.81 | KMT2A (0.36) | HPGDKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL9449086 | 0.81 | GABRA1 (0.41) | KDM4EGAA | |
| SCHEMBL9449116 | 0.81 | KMT2A (0.41) | ALDH1A1GAACHRM2CHRM4CHRM5 | |
| SCHEMBL9449289 | 0.80 | KMT2A (0.38) | KDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL9448798 | 0.80 | NOS3 (0.46) | KDM4EALDH1A1GAACHRNA7 | |
| SCHEMBL9449197 | 0.79 | CTSV (0.47) | HPGDKDM4ECHRNA7HSD17B10MCHR1 | |
| SCHEMBL9448924 | 0.79 | KDM4E (0.40) | HPGDKDM4EALDH1A1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227386-A | INDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-07-13 | — | — | US | disclosed |