Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449668 | 0.92 | TRPM8 (0.51) | CTSVCTSLMAOACHRNB2CHRNB4 | |
| SCHEMBL9449052 | 0.82 | KDM4E (0.43) | MAOACHRNA7MCHR1KDM4ELMNA | |
| SCHEMBL9449311 | 0.79 | IMPDH2 (0.50) | CTSVCTSLCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9449042 | 0.79 | HPGD (0.35) | CHRNA7MCHR1KDM4EHPGDHSD17B10 | |
| SCHEMBL9448855 | 0.78 | CHRNA7 (0.49) | CHRNA7MCHR1 | |
| SCHEMBL9448864 | 0.78 | GAA (0.47) | CHRNA7KDM4ELMNAMAPTHTT | |
| SCHEMBL9448924 | 0.78 | KDM4E (0.40) | CHRNA7KDM4ELMNAMAPTHPGD | |
| SCHEMBL9449046 | 0.78 | KMT2A (0.36) | KDM4EMAPTHPGDHTTHSD17B10 | |
| SCHEMBL9448822 | 0.78 | KDM4E (0.47) | MCHR1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL9449116 | 0.78 | KMT2A (0.41) | CHRNA7MCHR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227386-A | INDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-07-13 | — | — | US | disclosed |