Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449197 | 0.92 | CTSV (0.47) | TRPM8MAPTKDM4ELMNAHPGD | |
| SCHEMBL9448822 | 0.86 | KDM4E (0.47) | MAPTKDM4EHPGDHSD17B10MAPKAPK2 | |
| SCHEMBL9448904 | 0.84 | KDM4E (0.41) | KDM4EHPGDHSD17B10MAPKAPK2 | |
| SCHEMBL9448767 | 0.82 | MCHR1 (0.50) | MAPTKDM4EHPGDHSD17B10MAPKAPK2 | |
| SCHEMBL9449477 | 0.79 | NOS3 (0.52) | TRPM8MAPTKDM4ECHRNB2CHRNB4 | |
| SCHEMBL9449189 | 0.79 | MCHR1 (0.40) | KDM4EHPGDHSD17B10MAPKAPK2 | |
| SCHEMBL9448855 | 0.78 | CHRNA7 (0.49) | CHRNA7 | |
| SCHEMBL9449097 | 0.78 | LMNA (0.40) | KDM4ELMNAHPGDHTTHSD17B10 | |
| SCHEMBL9449066 | 0.78 | CYP1A2 (0.40) | HSD17B10CHRNA7 | |
| SCHEMBL9448869 | 0.78 | MAPKAPK2 (0.41) | KDM4ELMNAHPGDHSD17B10MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227386-A | INDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-07-13 | — | — | US | disclosed |