Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.40 |
| ▸ | GSK3B | P49841 | 11/20 | 0.38 |
| ▸ | TDP2 | O95551 | 2/20 | 0.35 |
| ▸ | GNG2 | P59768 | 1/20 | 0.35 |
| ▸ | GNB1 | P62873 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528567 | 0.86 | ATM (0.40) | TDP2EPHX2 | |
| SCHEMBL9449454 | 0.81 | MAPT (0.49) | TDP2 | |
| SCHEMBL8923640 | 0.77 | TSHR (0.35) | TDP2EPHX2 | |
| SCHEMBL27362455 | 0.74 | TDP2 (0.34) | TDP2 | |
| SCHEMBL27532024 | 0.73 | PKM (0.43) | EPHX2PARP1 | |
| SCHEMBL27357288 | 0.72 | TDP2 (0.30) | TDP2 | |
| SCHEMBL2306726 | 0.72 | EPHX2 (0.59) | EPHX2 | |
| SCHEMBL9437729 | 0.71 | PTPN1 (0.40) | PTPN1GSK3BTDP2GNG2GNB1 | |
| SCHEMBL15106223 | 0.70 | NPC1 (0.58) | PTPN1GSK3BGNG2GNB1 | |
| SCHEMBL8786235 | 0.70 | MAOB (0.56) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234924-A | Hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-08-10 | — | — | US | disclosed |