Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TK1 | P04183 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27636538 | 1.00 | LMNA (0.38) | LMNATSHRTK1ALBPKM | |
| SCHEMBL27532981 | 1.00 | LMNA (0.38) | LMNATSHRTK1ALBPKM | |
| SCHEMBL1128956 | 0.81 | TK1 (0.48) | LMNATSHRTK1ALBPKM | |
| SCHEMBL1128958 | 0.81 | TK1 (0.48) | LMNATSHRTK1ALBPKM | |
| SCHEMBL3813740 | 0.80 | LMNA (0.41) | LMNATSHRTK1ALBPKM | |
| SCHEMBL28552184 | 0.79 | UMPS (0.34) | — | |
| Phosphoric Acid SCHEMBL9086402 | 0.77 | TK1 (0.39) | LMNATSHRTK1ALBPKM | |
| SCHEMBL12748586 | 0.75 | TYMP (0.33) | LMNATK1TYMP | |
| SCHEMBL4383154 | 0.72 | CYP1A2 (0.41) | LMNA | |
| SCHEMBL18258987 | 0.71 | LMNA (0.32) | LMNATSHRTK1ALBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569457-A1 | USE OF THIAZOLO- 2,3-A]ISOINDOLE DERIVATIVES AS ANTIVIRAL MEDICAMENTS AND NOVEL THIAZOLO- 2,3-A]ISOINDOLE DERIVATIVES. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-11-18 | — | — | EP | disclosed |
| EP-0556245-A1 | USE OF THIAZOLO-ISOINDOLINONE DERIVATIVES AS ANTIVIRAL MEDICAMENTS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-08-25 | — | — | EP | disclosed |