Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327839 | 0.97 | HTR1B (0.47) | HTR1BDRD2DRD4DRD3TUBB4A | |
| Benzoic Acid SCHEMBL9449941 | 0.91 | DRD2 (0.43) | HTR1BDRD2DRD4DRD3TUBB4A | |
| SCHEMBL9450319 | 0.88 | ADRB2 (0.51) | HTR1BDRD4DRD3HTR1AALDH1A1 | |
| SCHEMBL9133428 | 0.85 | DHPS (0.51) | HTR1BDRD2DRD4DRD3GAA | |
| SCHEMBL9132823 | 0.85 | DHPS (0.50) | HTR1BDRD2DRD4DRD3GAA | |
| Hydrochloric Acid SCHEMBL9739316 | 0.84 | DHPS (0.50) | HTR1BDRD2DRD4DRD3GAA | |
| Hydrochloric Acid SCHEMBL9132778 | 0.84 | DHPS (0.49) | HTR1BDRD2DRD4DRD3GAA | |
| SCHEMBL7328319 | 0.83 | HTR1B (0.47) | HTR1BDRD2DRD4DRD3TUBB4A | |
| SCHEMBL10570499 | 0.83 | HTR1A (0.45) | HTR1BDRD2DRD4DRD3GAA | |
| SCHEMBL7333097 | 0.83 | ADRB2 (0.57) | HTR1BDRD4DRD3HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182282-A | Antiarrhythmia agents | ROUSSEL UCLAF (FR) | 1993-01-26 | — | — | US | disclosed |
| US-5086070-A | 4-BENZYL-1H-INDOLES AND ANTI-ARRTHYMIC USE THEREOF | ROUSSEL UCLAF (FR) | 1992-02-04 | — | — | US | disclosed |