Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458824 | 0.84 | CTRB1 (0.49) | HTTPPARGCDC25ACDC25BHSD17B10 | |
| SCHEMBL9459542 | 0.81 | MAPT (0.45) | PPARGALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL9459027 | 0.81 | SLC7A5 (0.42) | ALDH1A1HPGDMMEMMEL1TAS1R3 | |
| SCHEMBL9459397 | 0.80 | L3MBTL1 (0.43) | PPARGHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9459549 | 0.77 | LMNA (0.40) | HTTPPARGHSD17B10ALDH1A1HPGD | |
| SCHEMBL9727438 | 0.75 | PAM (0.41) | HTTPPARGCDC25BALDH1A1HPGD | |
| SCHEMBL9459260 | 0.73 | GAA (0.45) | HTTALDH1A1MAPT | |
| SCHEMBL7398409 | 0.73 | CTRB1 (0.51) | PPARGALDH1A1 | |
| SCHEMBL9727344 | 0.72 | MAPT (0.42) | PPARGALDH1A1KDM4EMAPT | |
| SCHEMBL7367331 | 0.71 | PPARG (0.45) | HTTPPARGALDH1A1HPGDMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5232920-A | For treating hypertension and congestive heart failure in mammals | SCHERING CORPORATION (US) | 1993-08-03 | — | — | US | claimed |
| US-5232920-A | For treating hypertension and congestive heart failure in mammals | SCHERING CORPORATION (US) | 1993-08-03 | — | — | US | disclosed |