Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.42 |
| ▸ | PRKACA | P17612 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | PRKX | P51817 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | SGK2 | Q9HBY8 | 2/20 | 0.42 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459542 | 0.85 | MAPT (0.45) | L3MBTL1MAPK1ALDH1A1HPGDKMT2A | |
| SCHEMBL9459228 | 0.83 | CTRB1 (0.53) | L3MBTL1ROCK2RPS6KA5PRKACAMAPK1 | |
| SCHEMBL9458917 | 0.80 | HTT (0.42) | ALDH1A1HPGDPPARGHSD17B10LMNA | |
| SCHEMBL9459027 | 0.80 | SLC7A5 (0.42) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL9459549 | 0.78 | LMNA (0.40) | ALDH1A1HPGDKMT2APPARGHSD17B10 | |
| SCHEMBL9727438 | 0.76 | PAM (0.41) | L3MBTL1ALDH1A1HPGDPPARG | |
| SCHEMBL9459260 | 0.75 | GAA (0.45) | MAPK1ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL12518290 | 0.74 | CTSL (0.44) | L3MBTL1ROCK2RPS6KA5PRKACAMAPK1 | |
| SCHEMBL7398409 | 0.74 | CTRB1 (0.51) | L3MBTL1ALDH1A1PPARG | |
| SCHEMBL9727210 | 0.73 | ALDH1A1 (0.38) | ALDH1A1HPGDKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5232920-A | For treating hypertension and congestive heart failure in mammals | SCHERING CORPORATION (US) | 1993-08-03 | — | — | US | disclosed |