Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322293 | 0.90 | PPARG (0.38) | MAOBALDH1A1PPARGPPARACYP3A4 | |
| SCHEMBL9459542 | 0.87 | MAPT (0.45) | MAPTL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL9459027 | 0.80 | SLC7A5 (0.42) | MAPTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL9459549 | 0.78 | LMNA (0.40) | MAPTKMT2AALOX12CYP2C9TSHR | |
| SCHEMBL7398409 | 0.76 | CTRB1 (0.51) | L3MBTL1CYP2C9RAB9AALDH1A1PPARG | |
| SCHEMBL9727172 | 0.75 | NLRP3 (0.48) | CYP2C9ALDH1A1PPARACYP3A4 | |
| SCHEMBL9727232 | 0.75 | LMNA (0.43) | KMT2ACYP2C9PPARGPPARACYP3A4 | |
| SCHEMBL9727233 | 0.75 | LMNA (0.43) | KMT2ACYP2C9PPARGPPARACYP3A4 | |
| SCHEMBL9459260 | 0.75 | GAA (0.45) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9459397 | 0.73 | L3MBTL1 (0.43) | L3MBTL1KMT2AMEN1ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173506-A | For treating hypertension, congestive heart failure, edema or urogenital disorders in mammals | SCHERING CORPORATION (US) | 1992-12-22 | — | — | US | disclosed |