Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465629 | 0.88 | TLR9 (0.53) | ALDH1A1RAB9AKMT2AMEN1NPSR1 | |
| SCHEMBL9465107 | 0.86 | AVPR1B (0.53) | KMT2AMEN1TSHRMAPTAVPR1B | |
| SCHEMBL9464977 | 0.85 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9465745 | 0.80 | SLC2A1 (0.47) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9465008 | 0.78 | MAPT (0.47) | ALDH1A1KMT2AMEN1NPSR1USP2 | |
| SCHEMBL9464986 | 0.75 | LIPE (0.46) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9465413 | 0.73 | MEN1 (0.52) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9464969 | 0.73 | TSHR (0.46) | ALDH1A1KMT2AMEN1TSHRAVPR1B | |
| SCHEMBL9464852 | 0.73 | AVPR1B (0.53) | ALDH1A1KMT2AMEN1MAPTAVPR1B | |
| SCHEMBL9464655 | 0.71 | AVPR1B (0.47) | ALDH1A1KMT2AMEN1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |