Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464991 | 0.86 | ALDH1A1 (0.47) | AVPR1BMEN1LMNAMAPTKMT2A | |
| SCHEMBL9464852 | 0.86 | AVPR1B (0.53) | AVPR1BMEN1LMNAMAPTKMT2A | |
| SCHEMBL9465629 | 0.86 | TLR9 (0.53) | MEN1MAPTKMT2ASMN1; SMN2TLR9 | |
| SCHEMBL9465249 | 0.83 | MAPT (0.49) | AVPR1BMEN1LMNAMAPTKMT2A | |
| SCHEMBL9464655 | 0.79 | AVPR1B (0.47) | AVPR1BMEN1LMNAMAPTKMT2A | |
| SCHEMBL9465687 | 0.78 | SMN1; SMN2 (0.50) | AVPR1BMEN1LMNAMAPTKMT2A | |
| SCHEMBL9465102 | 0.77 | AVPR1B (0.42) | AVPR1BMEN1LMNAMAPTKMT2A | |
| SCHEMBL9464643 | 0.74 | AVPR1B (0.46) | AVPR1BMEN1LMNAMAPTKMT2A | |
| SCHEMBL9464598 | 0.74 | SMN1; SMN2 (0.46) | AVPR1BMEN1LMNAMAPTKMT2A | |
| SCHEMBL9464952 | 0.74 | MAPT (0.46) | AVPR1BMEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |