Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21082198 | 0.83 | POLB (0.50) | POLBMT-CO2SMN1; SMN2GAAMAPT | |
| SCHEMBL5277543 | 0.83 | POLB (0.50) | POLBMT-CO2SMN1; SMN2GAAMAPT | |
| SCHEMBL5277549 | 0.83 | POLB (0.50) | POLBMT-CO2SMN1; SMN2GAAMAPT | |
| SCHEMBL261210 | 0.74 | MT-CO2 (0.46) | POLBMT-CO2SMN1; SMN2GAAMAPT | |
| SCHEMBL2033213 | 0.73 | MT-CO2 (0.69) | POLBMT-CO2SMN1; SMN2GAAMAPT | |
| SCHEMBL6583074 | 0.71 | POLB (0.56) | POLBMT-CO2SMN1; SMN2GAAMAPT | |
| SCHEMBL19296877 | 0.71 | SMN1; SMN2 (0.61) | POLBSMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL9544841 | 0.69 | POLB (1.00) | POLBMT-CO2SMN1; SMN2GAAMAPT | |
| SCHEMBL27494093 | 0.67 | RAB9A (0.43) | POLBSMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL7054325 | 0.67 | POLB (0.71) | POLBMT-CO2MAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5097783-A | — | — | None | — | — | JP | disclosed |
| JP-H0597783-A | 2-CYCLOHEXENONE COMPOUND AND CEREBRAL FUNCTION IMPROVER COMPRISING THE SAME COMPOUND AS ACTIVE INGREDIENT | NIKKEN CHEM CO LTD | 1993-04-20 | — | — | JP | disclosed |