Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.60 |
| ▸ | DRD1 | P21728 | 4/20 | 0.60 |
| ▸ | DRD3 | P35462 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17299377 | 0.88 | ALDH1A1 (0.64) | DRD2DRD1DRD3HTR1AALDH1A1 | |
| SCHEMBL17289305 | 0.88 | ALDH1A1 (0.64) | DRD2DRD1DRD3HTR1AALDH1A1 | |
| Bromide SCHEMBL17291153 | 0.87 | ALDH1A1 (0.65) | DRD2DRD1DRD3HTR1AALDH1A1 | |
| SCHEMBL30004318 | 0.84 | DRD2 (0.72) | DRD2DRD1DRD3HTR1AALDH1A1 | |
| SCHEMBL2554856 | 0.84 | DRD2 (0.72) | DRD2DRD1DRD3HTR1AALDH1A1 | |
| SCHEMBL3265051 | 0.84 | DRD2 (0.72) | DRD2DRD1DRD3HTR1AALDH1A1 | |
| SCHEMBL12877906 | 0.79 | DRD2 (0.80) | DRD2DRD1ALDH1A1MAPTKDM4E | |
| SCHEMBL12877888 | 0.76 | DRD2 (0.75) | DRD2DRD1DRD3HTR1AALDH1A1 | |
| SCHEMBL21901282 | 0.74 | KDM4E (0.80) | DRD2DRD1DRD3HTR1AALDH1A1 | |
| SCHEMBL12877903 | 0.73 | DRD2 (0.72) | DRD2DRD1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202502-A | Using b-halodiiso-2-ethylapopinocampheylborane as reducing agent | ALDRICH CHEMICAL COMPANY, INC. (US) | 1993-04-13 | — | — | US | claimed |
| US-5159116-A | Reducing agents in the asymmetric reduction of ketones to optically active alcohols | ALDRICH CHEMICAL COMPANY, INC. (US) | 1992-10-27 | — | — | US | claimed |
| US-9233966-B2 | Preparation of ticagrelor | DR. REDDY'S LABORATORIES LIMITED (IN) | 2016-01-12 | — | — | US | disclosed |
| US-20150073146-A1 | PREPARATION OF TICAGRELOR | DR. REDDY'S LABORATORIES LIMITED (IN) | 2015-03-12 | — | — | US | disclosed |
| EP-2834247-A2 | PREPARATION OF TICAGRELOR | Dr. Reddy's Laboratories Ltd. (IN) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013150495-A2 | PREPARATION OF TICAGRELOR | DR. REDDY'S LABORATORIES LIMITED (IN) | 2013-10-10 | — | — | WO | disclosed |
| US-5258384-A | Antidote for effects of cocaine, appetite suppressants | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1993-11-02 | — | — | US | disclosed |
| US-5220072-A | Reacting 2-ethylapopinene enantiomorph with haloborane-methyl sulfide complex | ALDRICH CHEMICAL CO., INC. (US) | 1993-06-15 | — | — | US | disclosed |
| US-5202502-A | Using b-halodiiso-2-ethylapopinocampheylborane as reducing agent | ALDRICH CHEMICAL COMPANY, INC. (US) | 1993-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073146-A1 | PREPARATION OF TICAGRELOR | CYP3A4, CYP2C19, TBXAS1 | DRD2 2546/4885DRD1 3507/4885DRD3 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.