Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | DRD2 | P14416 | 7/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.64 |
| ▸ | PKM | P14618 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | THPO | P40225 | 2/20 | 0.64 |
| ▸ | RGS12 | O14924 | 1/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | G6PD | P11413 | 3/20 | 0.62 |
| ▸ | GMNN | O75496 | 2/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17289305 | 1.00 | ALDH1A1 (0.64) | ALDH1A1MAPTDRD2MAPK1HSD17B10 | |
| Bromide SCHEMBL17291153 | 0.99 | ALDH1A1 (0.65) | ALDH1A1MAPTDRD2MAPK1HSD17B10 | |
| SCHEMBL9468568 | 0.88 | DRD2 (0.60) | ALDH1A1MAPTDRD2MAPK1HSD17B10 | |
| SCHEMBL2554856 | 0.85 | DRD2 (0.72) | ALDH1A1MAPTDRD2MAPK1HSD17B10 | |
| SCHEMBL30004318 | 0.85 | DRD2 (0.72) | ALDH1A1MAPTDRD2MAPK1HSD17B10 | |
| SCHEMBL3265051 | 0.85 | DRD2 (0.72) | ALDH1A1MAPTDRD2MAPK1HSD17B10 | |
| SCHEMBL27793240 | 0.81 | HTR1A (0.72) | ALDH1A1MAPTDRD2MAPK1HSD17B10 | |
| SCHEMBL11249155 | 0.81 | DRD2 (0.74) | MAPTDRD2KDM4EHPGDLMNA | |
| SCHEMBL11253334 | 0.80 | ALDH1A1 (0.82) | ALDH1A1MAPTDRD2MAPK1HSD17B10 | |
| SCHEMBL30543755 | 0.80 | ALDH1A1 (0.82) | ALDH1A1MAPTDRD2MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150342933-A1 | APORPHINE ALKALOID DERIVATIVE FOR ACTIVATING AMP-DEPENDENT PROTEIN KINASE | ZIH YUAN TANG BIOTECHNOLOGY CO., LTD. (TW) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150342933-A1 | APORPHINE ALKALOID DERIVATIVE FOR ACTIVATING AMP-DEPENDENT PROTEIN KINASE | PRKAB1, PRKAG1, PRKAB2 | ALDH1A1 1880/4885MAPT 1204/4885DRD2 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.