Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180113 | 0.81 | ADRA2A (0.44) | CTSLALDH1A1MAPTADRA2APNMT | |
| SCHEMBL3920383 | 0.81 | ALDH1A1 (0.50) | CTSLALDH1A1MAPTADRA2APNMT | |
| SCHEMBL3925257 | 0.81 | HTR1D (0.44) | CTSLALDH1A1MAPTADRA2APNMT | |
| SCHEMBL12920004 | 0.81 | ALDH1A1 (0.46) | CTSLALDH1A1MAPTADRA2APNMT | |
| SCHEMBL14159974 | 0.81 | LMNA (0.46) | CTSLALDH1A1MAPTADRA2APNMT | |
| SCHEMBL768764 | 0.81 | ALDH1A1 (0.54) | CTSLALDH1A1MAPTADRA2APNMT | |
| SCHEMBL3506059 | 0.81 | ALDH1A1 (0.48) | CTSLALDH1A1MAPTADRA2APNMT | |
| SCHEMBL9470708 | 0.78 | MAPT (0.43) | CTSLALDH1A1MAPTADRA2APNMT | |
| SCHEMBL30288495 | 0.76 | CA2 (0.51) | ALDH1A1MAPTADRA2APNMTTDP1 | |
| SCHEMBL376278 | 0.74 | PNMT (0.47) | ALDH1A1MAPTPNMTGPR35TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377548-B1 | PROCESS FOR NITRATING PHOTOCLEAVABLE COMPOUNDS | MEDICAL RES COUNCIL (GB) | 2009-02-18 | — | — | EP | disclosed |
| EP-1161418-B1 | 1-ACYL-7-NITROINDOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PHOTOCLEAVABLE PRECURSORS | MEDICAL RES COUNCIL (GB) | 2005-12-28 | — | — | EP | disclosed |
| US-20040171846-A1 | Process for nitrating photocleavable compounds | MEDICAL RESEARCH COUNCIL (GB) | 2004-09-02 | — | — | US | disclosed |
| US-6765014-B1 | DRUG DELIVERY OF NEUROACTIVE AMINO ACIDS OR METAL CHELATORS | MEDICAL RESEARCH COUNCIL (GB) | 2004-07-20 | — | — | US | disclosed |
| EP-1377548-A1 | PROCESS FOR NITRATING PHOTOCLEAVABLE COMPOUNDS | MEDICAL RESEARCH COUNCIL (GB) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083639-A1 | PROCESS FOR NITRATING PHOTOCLEAVABLE COMPOUNDS | MEDICAL RESEARCH COUNCIL (GB) | 2002-10-24 | — | — | WO | disclosed |
| EP-1161418-A1 | 1-ACYL-7-NITROINDOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PHOTOCLEAVABLE PRECURSORS | MEDICAL RESEARCH COUNCIL (GB) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055133-A1 | 1-ACYL-7-NITROINDOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PHOTOCLEAVABLE PRECURSORS | MEDICAL RESEARCH COUNCIL (GB) | 2000-09-21 | — | — | WO | disclosed |
| EP-0089426-B1 | 2-AMINO-6-BIPHENYLACETIC ACIDS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-06-11 | — | — | EP | disclosed |
| US-4159271-A | CYCLIZATION OF A 2-HALOGENOPHENETHYLAMINE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1979-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171846-A1 | Process for nitrating photocleavable compounds | NOS2, SOD1, NIT2 | CTSL 4351/4885ALDH1A1 175/4885MAPT 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.