Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476966 | 0.86 | ESR1 (0.40) | L3MBTL1LMNANR1I2HSD11B1ALDH1A1 | |
| SCHEMBL9475806 | 0.76 | ESR1 (0.42) | NR1I2HSD11B1KMT2AMEN1 | |
| SCHEMBL9475204 | 0.76 | LIMK1 (0.44) | L3MBTL1LMNATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL11561748 | 0.72 | DPP4 (0.40) | LMNAALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL5376574 | 0.71 | LMNA (0.40) | LMNAALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9474357 | 0.71 | LMNA (0.33) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11561636 | 0.70 | DPP4 (0.39) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8783273 | 0.70 | L3MBTL1 (0.49) | L3MBTL1LMNAHSD11B1GAAALDH1A1 | |
| SCHEMBL9492475 | 0.70 | MGLL (0.42) | L3MBTL1LMNAALDH1A1TSHRKMT2A | |
| SCHEMBL9502987 | 0.70 | ALDH1A1 (0.48) | LMNAGAAALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258361-A | Antigrowth agents biological | ROHM AND HAAS COMPANY (US) | 1993-11-02 | — | — | US | disclosed |