Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12282201 | 0.84 | CES2 (0.45) | — | |
| SCHEMBL2008587 | 0.80 | NR1H4 (0.53) | MAPTNR1H4HDAC1ALDH1A1LMNA | |
| SCHEMBL7306864 | 0.80 | ALDH1A1 (0.42) | KMT2AMEN1MAPTNR1H4ALDH1A1 | |
| SCHEMBL3578941 | 0.79 | ESR1 (0.54) | KMT2AALDH1A1 | |
| SCHEMBL7372260 | 0.79 | MAPT (0.44) | KMT2AMEN1MAPTNR1H4HDAC1 | |
| SCHEMBL8307755 | 0.79 | MAPT (0.44) | KMT2AMEN1MAPTNR1H4HDAC1 | |
| SCHEMBL2390293 | 0.78 | SLC6A3 (0.46) | KMT2AMAPTALDH1A1LMNARECQL | |
| SCHEMBL17309222 | 0.78 | RAB9A (0.49) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12742297 | 0.78 | KMT2A (0.48) | KMT2AMEN1MAPTHDAC1ALDH1A1 | |
| SCHEMBL1154849 | 0.78 | L3MBTL1 (0.49) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243066-A | ALKYL 2-ARYL-2,2-DIALKOXYACETATES, THE PREPARATION THEREOF AND A METHOD OF USING THEM FOR PREPARING ARYLGLYOXYLIC ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |